Polycystic ovary syndrome, part 1

Polycystic ovary syndrome, part 1 Infertility is a painful and often affects about 1 in 6 couples. The statistics confirm that the incidence of infertility is increasing. Most couples, however, are in search of help and advice more accessible and effective treatments. After working in the field of specialization of infertility fifteen years, I understand that many couples find a diagnosis of polycystic ovary syndrome (Pcos) confusing and difficult understand.PCOS is highly variable and that the disorder has been described for first time by Drs. Stein and Leventhal in 1935. Have identified a group of infertile women who have menstrual disturbances, and enlarged ovaries (now known as polycystic ovary). It also describes hirsutism and obesity group.Not that all women with polycystic ovaries, however, these features are presented. JW Goldzieher and JA Green (1962) reported that in women with polycystic ovaries surgically proven, 20% had no menstrual irregularities, 50% are obese and 31% were not hirsuta. Polson et. al. (1988) confirmed these findings and reported that polycystic ovaries were found in 22% of the normal population, ie women who had not sought treatment for menstrual disorders, infertility hirsutism.PCOS or may be classified in three criteria : 1. Clinical presentation,   2nd Biochemical characterization and   3rd Characterization of ovarian abnormalities.It is that these three criteria are important for the diagnosis and classification of women with Pcos PCOS.Most have a history of age but develop normal menstrual cycles irregular since menarche. Clearly, then, that some women presenting with infertility may have physiological problems in their teenage years and may be anticipated the impact this would have on their reproductive health in the future. Women with Pcos often excessive growth of hair and be overweight. Yen (1980) noted that over 80% of women are obese with Pcos first start of puberty. Although obesity is frequently associated with this disease is not clear whether an intrinsic or a predisposing condition such as weight loss is often associated with the correction of hormonal disorders and restore regular ovulation.As Pcos a high prevalence in families of people affected, the syndrome may have a genetic component (and Hauge. al., 1988). Hypertension, diabetes, insulin resistance and obesity occur more often in families of Pcos women, while the anomalies and testicular endocrine function were described in male relatives. A recent study has identified the family of SOP premature baldness in men of the family, as the male phenotye of PCOS.Biochemical evaluation of women with Pcos will be discussed and provides for the assessment of hormone levels in the blood. Upon delivery of a woman is between 200,000 and 400,000 primary follicles in each ovary. After a cycle of release of hormones produced by the menstrual cycle, one follicle will mature during each primary cycle and a mature egg will be released. The follicle stimulating hormone (FSH) and Leutenising hormone (LH) Gonadotrophic are hormones released by the anterior pituitary gland that act directly on the hormones ovary.These first antral follicles antral or Graafian follicles and everyone seems to exert its effects in various positions within follicle. Granulosa cells bind FSH follicles, while only in theca cells bind LH Inteational. The proliferation of granulosa cells and thecal cause an increase in follicular phase follicle growth size.During the increase in androgens and the synthesis of cholesterol and acetate this conversion is stimulated by LH as the follicle continues to increase in size of synthetic estrogen? s increases and the increase in emissions advanced follicular steroids in practice. These steroid feedback to the pituitary and this leads to a progressive reduction of circulating FSH and therefore limits the development of new follicles.   Estrogen in conjunction with FSH plays a crucial role in follicle towards the second phase growth.Together that stimulate the appearance of binding sites for LH in the outer layer of cells that lacked granlosa them beforehand. The Graafian follicle to die unless a brief wave of gonadotropin levels coincides with the appearance of LH receptors. The increase in LH has two effects. First, ovulation occurs and the egg is expelled from the follicle and, secondly, it changes the set of follicle endocrinology, forming a corpus luteum after ovulation. The corpus luteum   then secretes estrogen and progesterone, which support the development of a embryo.Carole Mallinson is a health professional with over 15 years of experience   in the field of male and female infertility. Join them and gain access to the range of medical products in this niche with rights fullresale